Advancing Neurobiology Research with Precision Mouse Models & Studies

Simplify your neuromuscular, neurodevelopmental, and neurodegenerative disease research process and studies. Partner with us to enhance the precision, efficiency, and impact of your preclinical studies.

With leading-edge science, a wide range of neuroscience mice, and a collaborative approach, we provide the resources and expertise you need to advance novel therapies and make a meaningful impact in human health. Our dedicated team of preclinical neurobiology experts has unparalleled experience with unique neurobiology research mouse models.

Whether your focus is on neurobiology animal research, behavioral analysis, or molecular studies, we provide the tools and expertise you need to succeed.

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Neuroscience Assays And Capabilities

JAX study directors and technicians are experts at conducting translationally-relevant molecular, physiological, and behavioral assessments. By conducting your studies with JAX Preclinical Research Services, you'll have access to robust neurobiology solutions, expert guidance, custom study designs, and reliable data. Work with our experienced scientists on custom study designs to include the most relevant measures and models of your choice.

Histopathology & Biomarker Assessment

Protein expression analysis
Gene expression analysis
Copy number validation
Inflammation & Fibrosis assessment
Neuromuscular Junction assessment
Axon quantification

Motor & Coordination Assays

Dynamic Weight Bearing
Gait Analysis with Treadmill
Forced Treadmill
Grip Strength
Homecage Wheel Running
Rotarod
Wire Hang

General Behavior & Fine Motor

Neuroscore/Clinical Observation
Frailty Screen
Open Field Exploratory
Seizure Susceptibility (ECT)
Whole Body Plethysmography (WBP)
Circadian Activity Monitoring
Audiogenic Seizure Activity
Induced Grooming

Cardiology & Physiology

Auditory Brainstem Response
Blood Pressure, Non-Invasive
Cardiac Ultrasound, High Frequency
DSI EEG/EMG-Seizures
DSI EEG/EMG-Sleep
Electrocardiogram, Anesthetized
Electroretinography
Gross Morphology Photography
Piezoelectric Sleep Monitoring

Electrophysiology

Motor Unit Number Estimation (CMAP & RNS)
Nerve Conduction Velocity (NCV)
Force Reading

iPSCs and Their Value in Tackling Neurodegenerative Disease Research

Induced pluripotent stem cells (iPSCs) have become an invaluable tool for modeling neurodegenerative disorders and are increasingly used in drug discovery/preclinical trials, safety pharmacology, and toxicology.

Dr. Mark Cookson, senior investigator at the NIH National Institute on Aging, talks about the unique aspects of this collection and how it can benefit the wider scientific community in their shared quest to understand and fight ADRD.

Learn how to enhance neurodegenerative research with iPSCs below:

Watch the Video about iPS Cells