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JAX Frontend Platform

Personalized Medicine

Since its inception, The Jackson Laboratory has led the discovery of causes, treatments and cures for some of humankind's most devastating genetic diseases.

Today, we are speeding the path of discovery from the laboratory bench to clinical care. We are combining the skills and knowledge of our scientists with our institutional strengths in disease modeling and bioinformatics, connecting genetics to genomics, and using our unparalleled knowledge of mouse models of disease to understand the human condition.

JAX research programs are leading efforts to improve human health worldwide.

Addiction

Addiction is a chronic illness, with genetic, environmental and social aspects. JAX researchers are at the forefront of understanding the genetic factors involved in individuals’ vulnerability to addiction.

Aging

JAX researchers are using genomic technologies and specialized mouse models to decipher the changes that occur as a consequence of aging in order to extend our health span, delay age-related health issues, repair damaged organs and improve our quality of life.

Alzheimer's And Other Dementias

Using genomic technologies and specialized mouse models to develop preventative therapies, JAX scientists aim to stop Alzheimer’s before it starts.

Cancer

Driven by the desire to eradicate cancer, we are leading the future of cancer treatments by combining computational expertise with our unparalleled knowledge of mouse genetics.

Cardiovascular

JAX researchers are exploring the genes associated with an increased risk for cardiovascular disease and seeking new ways to prevent and repair heart damage.

Computational Biology

Scientists are generating data of such magnitude and complexity that advanced computational methods are vital for data analysis, management and dissemination.

Diabetes

JAX researchers investigate the processes that lead to failure to produce insulin in type 1 diabetes and loss of insulin production in type 2 diabetes.

Immune Diseases

To thwart infectious diseases and other potential threats to health, each of us carries an amazingly sophisticated set of weapons. The immune system mounts targeted attacks against specific pathogens and protects us against environmental insults. But what happens when this system goes haywire?

Microbiome

JAX researchers are exploring the effect on health and disease of the microorganisms that outnumber human cells 10 to 1.

Obesity

At the institution that first established the genetic and hormonal basis for obesity, JAX researchers probe for ways to prevent diabetes and other obesity-related conditions.

 

Regenerative Medicine

The promise of regenerative medicine is the potential for growing healthy new tissues and organs to replace those damaged by disease or injury, using the patient's own cells so the body does not reject the new material.

  Unlocking the power of stem cellsProfessor Martin Pera, Ph.D. combines his extraordinary expertise in human stem cell biology with powerful JAX resources in order to bring about breakthroughs in reproductive therapies and regenerative medicine.

Reproduction and Infertility

Understanding the complex genetic events in healthy reproduction and early development, for insights into fertility problems, birth defects and genetic diversity.

Vision research

JAX researchers are shedding light on the mechanisms of eye diseases such as glaucoma and macular degeneration, as well as Alzheimer’s and other neurodegenerative diseases – treating the eye as a window

Personalized medicine and you

We identify the genetic and molecular bases of disease and marshal our strengths in genomics and disease modeling to discover individualized treatments and cures so that medicine is more precise, predictable and personal.

Personal Stories

Meet the happy cancer warrior

Betty Walls is fighting cancer with an upbeat attitude and advanced genomic treatment.

What are the early signs of Alzheimer's and am I at risk?

Will I get Alzheimer's? This is a common concern among many. Here, we explain who is at risk and why the answer may be in your genes.

The gene detective

By harnessing the most advanced data-mining tools, JAX Professor Carol Bult is leading the hunt for suspect genes that contribute to a common, deadly birth defect

Advanced care for Maine's most isolated cancer patients

The Jackson Laboratory's partnership with the Jefferson Cary Cancer Center brings Maine Cancer Genomics Initiative options to Aroostook County.

A rare disease calls for a unique mouse model

For the rarest of rare genetic conditions, a one-of-a-kind mouse could light a path to new treatments.

A cure for Caroline

JAX Professor Robert Burgess and collaborators are developing personalized gene therapy for a Texas child suffering from a neuromuscular disease.

Researchers are counting on JAX

Can we count on you?

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