The Jackson Laboratory

Mouse Breeding Services

JAX® Breeding Services helps make managing your mouse colonies easy, hands-off, and affordable. Our experts can strategically expand and earmark colonies of all strains, including JAX's cryopreserved strains, to align with and be dedicated solely to your research. We also offer specialized diets and aging services to give you greater control over important variables in your study. Partner with JAX to provide the mice you need, when you need them, and maintain the colony for you throughout your study.

Key benefits

  • Breed your mice or build a colony from the world's largest repository of genetically engineered mouse strains, all maintained using high health standards.
  • Over 80 years' experience in mouse husbandry at your service, including expertise in managing even the most demanding strains.
  • Dedicated project management staff and the JAX Connect™ portal are available to help you navigate capacity and facility challenges without impacting your mice.
  • Scientific support from world-renowned researchers, veterinarians, highly-trained technicians.
  • Need help creating your model before entering it into a breeding colony? Consider JAX Model Generation Services

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JAX Mouse Breeding Services
JAX Mouse Breeding Services - Small to Complex Projects

Small to Complex Projects

JAX has decades of success working with strains of all difficulties and can design an optimal breeding strategy for you.

JAX Mouse Breeding Services - Study Ready, Delivered when Needed

Study-Ready, Delivered when Needed

Stay updated on the status of your mice and communicate updates through the JAX Connect™ portal

JAX Mouse Breeding Services - High Health Standards

High Health Standards

JAX® Mice are maintained in Pathogen & Opportunistic-Free animal rooms to ensure clean and healthy mice for a reproducible study.

Types of Breeding Projects

No two breeding projects at JAX are the same. From small, simple crosses to large, multi-generational, multi-allelic projects, we have remained at the ready for researchers supporting continuous scientific progress. The resulting mice are delivered in a high-health status (Specific and Opportunistic Pathogen Free) and at the age, sex, and genotype of your choosing to ensure the highest rate of reproducibility for your study. Common breeding services and projects include:

Custom BreedingAllows you to breed your own mice at scale. JAX excels at complex strain breeding (Cre-lox, multiple genes, strain issues with infertility and lethality, etc.).
Dedicated SupplyCreate researcher-specific cohorts of JAX® Mice, which can be helpful for creating live colonies of JAX cryopreserved strains or for sharing mice among collaborators and different institutions.
IVF ExpansionRapidly generate large quantities of mice to expand your unique colonies or to generate cohorts of JAX® Mice that are only available in limited supply saving you valuable time.
Learn more about our IVF Expansion services 
Model Generation Custom BreedingSupports and nurtures novel strains generated through our Model Generation Services.
Speed CongenicCarry your chromosomal changes to a parent inbred strain through multiple generations of backcrossing and offset the impact of genetic drift.

Additional Colony Management Services

In addition to the core breeding services above, JAX can also maintain different aging, feeding, surgical requirements, or preclinical services for your study:

  • Aging Services care for your mice for a significantly longer amount of time until they are delivered to you at an agreed-upon age.
  • Preclinical Services have study-ready cohorts delivered to your lab or seamlessly transitioned into studies with our Preclinical Services Team.
  • Custom Diet can be fed to your mice, upon request and when provided by you. JAX has relationships with science diet providers and formulators to help you develop a diet (high fat, customized nutrients, etc.) that can be supplied at the scale needed for any project.
  • Surgical Services are available for a variety of procedures, performed by our expert in-house surgeons. Learn more about Surgical Services
  • Blood, Tissues and Organs can be surgically harvested and prepared fresh for direct shipment. Learn more about Mouse Tissues and Organs
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Support Reproducibility & the 3R's with Effective Mouse Colony Management

Support Reproducibility & the 3R's with Effective Mouse Colony Management

No one knows JAX Mice® strains like JAX. In this webinar we share environmental and genetic factors that impact mouse breeding performance and best practices for effective record keeping and organization in mouse colony management. We also will dive into the importance of genotyping and resources for PCR troubleshooting.

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JAX Connect™

JAX Connect™ is an intuitive and powerful online colony management tool that saves you time without sacrificing control of your mice. 24-hour access to mouse-level colony information gets you answers you need when you need them. Direct collaboration features empower you to direct action for your colony from within the system.

Features include:

  • Facilitates direct communication between you and your project manager to remain aligned on breeding project needs.
  • Up-to-date mouse-level information provides all necessary information at your fingertips.
  • Individual or group-level permissions give you control over colony visibility within your organization.

See how one of our Breeding partners, Denali, was able to reduce excess animal production using colony metrics and the JAX Connect™ platform.
See The Data

JAX Connect™ Online Colony Management Tool

JAX Gold Standard

At The Jackson Laboratory, we are committed to maintaining the highest animal care and health standards across all our mouse colonies. All JAX® Mice are bred and maintained in specialized barrier facilities that are categorized based on the specific organisms they exclude. Our clinical medicine and pathology programs are integral to our mouse health management strategy such as rigorous cleaning and disinfection protocols for animal rooms and equipment and ensure a pathogen-free environment as well as evaluating the pathological effects of newly identified gene mutations. The Diagnostic Program is dedicated to ensuring the health of JAX® Mice from importation to shipment.

View the JAX Animal Health Program

JAX Gold Standard - Maintaining the Highest Animal Care and Health Standards

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