Settings
Save and close
Antibodies are versatile tools for the treatment of diseases such as cancer, immunological disorders, and central nervous system (CNS) diseases. The creation and evaluation of antibody therapeutics requires sophisticated tools and in-depth expertise. JAX offers next-generation transgenic mice for monoclonal and bispecific antibody discovery, and a suite of humanized mouse models for the evaluation of pharmacokinetics, efficacy, and safety. Look to JAX for the best models and services to accelerate your antibody discovery programs.
Get the most clinically translational PK data for your antibody with JAX’s genetically-humanized FcRn platforms and move to the clinic faster. Work with us to find a model that suits your therapeutic’s configuration and immunogenicity and determine your ideal first-in-human dose.
Leverage JAX’s unrivaled NSG® mice engrafted with human PBMCs to examine donor-to-donor differences and engage human-specific targets.
Select from our range of immune-humanized mouse models to ensure the right immune cell populations for your therapeutic’s mode of action. Then test the safety and efficacy of your antibody in the presence or absence of a PDX or CDX tumor.
Sign Up | JAX Pulse
Stay informed about our events, blogs and videos, and cutting-edge research platforms.