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In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches -- gene therapy and bone marrow transplantation – to alleviate symptoms of multiple sulfatase deficiency (MSD), an ultra-rare genetic disease with no cure.
Learn moreThe Jackson Laboratory (JAX) advanced its mission to improve human health through game-changing contributions to science and education over the last year...
Combining genetic therapy and bone marrow transplantation may offer comprehensive treatment solution for multiple sulfatase deficiency.
Mice with a genetically pure background are susceptible to severe SARS-CoV-2 infection.
Researchers at The Jackson Laboratory are part of multi-disciplinary teams that won $60 million in ARPA-H funding to study 3-D tumor models and personalized drugs.
The AI-powered home-cage monitoring solution is poised to enhance preclinical research efficiency and improve the translation of findings to clinical settings.
Researchers at The Jackson Laboratory have developed a new combination of imaging and computational methods to study connections between immune cells in breast cancer and melanoma.
Researchers at The Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence to design thousands of new DNA switches that can precisely control the expression of a gene in different cell types.
Researchers at The Jackson Laboratory conduct pivotal study into aging and lifespan to uncover new details about how diets might make people live longer — but also their negative side effects.
Some genetic factors predisposing people to diabetes might change the way pancreatic cells respond to molecular stress, researchers at JAX discovered.
The new funding will help support the first-of-its-kind single-cell mass spectrometer in Maine, and one of the first in the country.
Through interactive, case-based lessons, the series empowers cardiology clinicians to move beyond a one-size-fits all approach, enabling them to adopt more targeted management strategies for their patients.
Mary Dickinson, Ph.D., executive vice president and chief scientific officer at The Jackson Laboratory, has joined the ranks of Fellow of the American Association for the Advancement of Science, a distinguished lifetime honor within the scientific community.
Digital education modules to be developed by the genomic education team at The Jackson Laboratory aim to prepare Connecticut State Community College students for careers in bioscience and strengthen the state's workforce.
The collaboration will allow for a more rapid and efficient approach to the identification and pre-clinical evaluation of potential drug candidates across multiple diseases to advance into clinical testing.
Diverse mouse models show promise in how we understand and treat diseases, offering a significant improvement over standardized but limited mouse and cellular models.
This recognition by the Society is its highest honor in the academic fields of arts, social sciences, humanities and sciences.
The Jackson Laboratory breakthrough could accelerate efforts to understand and treat dementia.
The Jackson Laboratory has developed a computer vision-based method to accurately and continuously measure mouse body mass, offering a new resource for researchers that promises to enhance the quality of a wide range of preclinical studies.
Research offers first ranking of relative role and significance of every known gene and protein in development of Alzheimer's.
The role of gut-brain interaction in developing new alcohol use disorder treatments.
Hematopoietic stem cells age differently in genetically identical mice, offering new pathways for interventions to preserve health with aging.
Study explores impact of workplace genetic testing on employee health behaviors.
Reengergizing exhausted T cells can kickstart immune system to fight cancer.
Wild-derived mice could make it easier to draw conclusions about the effectiveness of new treatments or pharmaceuticals in humans.
Partnership to expedite antibody discovery and derisk the development of vital new therapies.
Dickinson's research background coupled with her successful executive leadership will help drive major initiatives and research priorities at a time of rapid growth.
Maine cancer patients experienced better outcomes following genomic tumor testing to guide targeted therapy strategies; but a gap between testing and clinical delivery still exists.
The new funding will help support the first-of-its-kind single-cell mass spectrometer in Maine, and one of the first in the country.
A new protocol sets the stage for researchers to directly compare mouse and human cells to more closely approximate human health conditions.