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Damien Chaussabel, Ph.D.

Principal Computational Scientist

Development of approaches and resources for the analysis, visualization and functional interpretation of large-scale immunological profiling datasets.

Location

Farmington, CT

Contact

207-288-6000

[email protected]

My research has focused on blood transcriptomics and its application in patient-based research. My primary role at the Jackson Laboratory is to support the development of systems immunology and immunoinformatic research capacity – including through the implementation of training programs and the support of projects and investigators conducting immunology research at Jax.

Damien Chaussabel on ORCID

Selected Publications

106Castaneda DC, Jangra S, Yurieva M, Martinek J, Callender M, Coxe M, Choi A, García-Bernalt Diego J, Lin J, Wu TC, Marches F, Chaussabel D, Yu P, Salner A, Aucello G, Koff J, Hudson B, Church SE, Gorman K, Anguiano E, García-Sastre A, Williams A, Schotsaert M, Palucka K. Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia. iScience. 2023 Aug 18; 26(8):107374
Gofshteyn JS, Mansfield L, Spitznagle J, Balasubramanian P, Cardenas J, Miller T, Gu J, Wang X, Punaro M, Fuller J, Nassi L, Stewart K, Ohouo M, Stagnar C, Baisch J, Walters L, Wang Y, Yan H, Rinchai D, Chaussabel D, Caielli S, Hong S, Onel K, Wright T, Pascual V. Association of Juvenile Dermatomyositis Disease Activity With the Expansion of Blood Memory B and T Cell Subsets Lacking Follicular Markers. Arthritis Rheumatol. 2023 Jul; 75(7):1246-1261
40Al Ali F, Marr AK, Tatari-Calderone Z, Alfaki M, Toufiq M, Roelands J, Syed Ahamed Kabeer B, Bedognetti D, Marr N, Garand M, Rinchai D, Chaussabel D. Organizing training workshops on gene literature retrieval, profiling, and visualization for early career researchers. F1000Res. 2021; 10:275
87Roelands J, Kuppen PJK, Ahmed EI, Mall R, Masoodi T, Singh P, Monaco G, Raynaud C, de Miranda NFCC, Ferraro L, Carneiro-Lobo TC, Syed N, Rawat A, Awad A, Decock J, Mifsud W, Miller LD, Sherif S, Mohamed MG, Rinchai D, Van den Eynde M, Sayaman RW, Ziv E, Bertucci F, Petkar MA, Lorenz S, Mathew LS, Wang K, Murugesan S, Chaussabel D, Vahrmeijer AL, Wang E, Ceccarelli A, Fakhro KA, Zoppoli G, Ballestrero A, Tollenaar RAEM, Marincola FM, Galon J, Khodor SA, Ceccarelli M, Hendrickx W, Bedognetti D. An integrated tumor, immune and microbiome atlas of colon cancer. Nat Med. 2023 May; 29(5):1273-1286
24Preechanukul A, Yimthin T, Tandhavanant S, Brummaier T, Chomkatekaew C, Das S, Syed Ahamed Kabeer B, Toufiq M, Rinchai D, West TE, Chaussabel D, Chantratita N, Garand M. Abundance of ACVR1B transcript is elevated during septic conditions: Perspectives obtained from a hands-on reductionist investigation. Front Immunol. 2023; 14:1072732
68Rinchai D, Deola S, Zoppoli G, Kabeer BSA, Taleb S, Pavlovski I, Maacha S, Gentilcore G, Toufiq M, Mathew L, Liu L, Vempalli FR, Mubarak G, Lorenz S, Sivieri I, Cirmena G, Dentone C, Cuccarolo P, Giacobbe DR, Baldi F, Garbarino A, Cigolini B, Cremonesi P, Bedognetti M, Ballestrero A, Bassetti M, Hejblum BP, Augustine T, Van Panhuys N, Thiebaut R, Branco R, Chew T, Shojaei M, Short K, Feng CG, PREDICT-19 Consortium, Zughaier SM, De Maria A, Tang B, Ait Hssain A, Bedognetti D, Grivel JC, Chaussabel D. High-temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines. Sci Adv. 2022 Nov 11; 8(45):eabp9961
31Lukaszewski RA, Jones HE, Gersuk VH, Russell P, Simpson A, Brealey D, Walker J, Thomas M, Whitehouse T, Ostermann M, Koch A, Zacharowski K, Kruhoffer M, Chaussabel D, Singer M. Presymptomatic diagnosis of postoperative infection and sepsis using gene expression signatures. Intensive Care Med. 2022 Sep; 48(9):1133-1143
44Sharari S, Kabeer B, Mohammed I, Haris B, Pavlovski I, Hawari I, Bhat AA, Toufiq M, Tomei S, Mathew R, Syed N, Nisar S, Maacha S, Grivel JC, Chaussabel D, Ericsson J, Hussain K. Understanding the Role of GLUT2 in Dysglycemia Associated with Fanconi-Bickel Syndrome. Biomedicines. 2022 Aug 29; 10(9)
32Brown LG, Haack AJ, Kennedy DS, Adams KN, Stolarczuk JE, Takezawa MG, Berthier E, Thongpang S, Lim FY, Chaussabel D, Garand M, Theberge AB. At-home blood collection and stabilization in high temperature climates using homeRNA. Front Digit Health. 2022; 4:903153
32Hawari I, Ericsson J, Kabeer BSA, Chaussabel D, Alsulaiti A, Sharari SA, Maccalli C, Khan FA, Hussain K. Understanding the Mechanism of Diabetes Mellitus in a LRBA-Deficient Patient. Biology (Basel). 2022 Apr 18; 11(4)
24Huang SSY, Rinchai D, Toufiq M, Kabeer BSA, Roelands J, Hendrickx W, Boughorbel S, Bedognetti D, Van Panhuys N, Chaussabel D, Garand M. Transcriptomic profile investigations highlight a putative role for NUDT16 in sepsis. J Cell Mol Med. 2022 Mar; 26(5):1714-1721
37Toufiq M, Huang SSY, Boughorbel S, Alfaki M, Rinchai D, Saraiva LR, Chaussabel D, Garand M. SysInflam HuDB, a Web Resource for Mining Human Blood Cells Transcriptomic Data Associated with Systemic Inflammatory Responses to Sepsis. J Immunol. 2021 Nov 1; 207(9):2195-2202

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Damien Chaussabel, Ph.D.

Principal Computational Scientist

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Selected Publications