B10.mdx Physiological Data

C57BL/10ScSn-Dmd^mdx/J mice (001801), commonly called mdx, are the most published model of Duchenne’s muscular dystrophy. The mice carry a loss-of-function mutation in the dystrophin (Dmd) gene, and homozygotes show progressive cycles of muscle degeneration and regeneration starting at about three weeks of age.

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