Flow Cytometry Characterization Data for Immunodeficient JAX Strains

Flow cytometry characterization data are now available for thirteen immunodeficient JAX strains (000819, 002019, 007850, 001913, 001803, 001131, 001303, 005557, 013062, 007799, 002216, 003145, 001011). The levels of B cells, T cells (CD8 and CD4), and NK cells were measured in whole blood and spleen preparations.

View results and detailed protocol here.

Figure 1 Representative flow cytometry scatter plot showing the absence of CD19-positive B cells and CD3e-positive T cells in the peripheral blood of immunodeficient NOD.Cg-Prkdc^scidIl2rg^tm1Wjl/SzJ (“NSG”; 005557) female mice compared to the wildtype control strain, NOD/ShiLtJ (001976).

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Immunodeficient Mouse and Xenograft Host Comparison