The Unutmaz Lab investigates the biology of the human immune system.
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The Unutmaz Lab investigates the biology of the human immune system.
Our research primarily focuses on decoding the differentiation, activation and regulation of human T cells for optimal immune responses to infectious diseases and their perturbations during chronic diseases or aging. We have contributed to the understanding of how T cell subsets are disrupted during human diseases, especially during HIV infection. Our lab has made several seminal discoveries about the diversity and mechanisms of immune suppression mediated by regulatory T cells and effector functions of human Th17 cell subsets.