Membership

Associate Professor

Investigates how alternative RNA splicing contributes to cancer with the goal of identifying novel clinical biomarkers and targets for precision medicine.

Assistant Professor

Investigates the mechanisms and consequences of genomic rearrangements with a focus on repetitive elements. These lines of inquiry could find regions prone to instability in human cancers and lead to targets for therapy.

Research Scientist

A mouse's genetics are reflected in its phenotype, its measurable characteristics including appearance, behavior and physiology. We work on the Mouse Phenome Project, an international collaborative effort seeking to comprehensively characterize a large set of commonly used and genetically diverse strains of mice and other reference populations.

Associate Professor

Researches meiosis, the mechanisms of DNA damage detection and repair during normal development of gametes, and implications for fertility of cancer patients after radiation and chemotherapy.

Professor

Integrates computation and informatics with biomedical research. Makes knowledge about mouse models of human cancer  FAIR (findable, accessible, interoperable, reusable).

Assistant Professor

Researches the complex interactions of the tumor microenvironment with the host immune system. Focuses on immunometabolism of T and B cells, which play a vital role in fighting tumors.

Professor

Computational studies of cancer image and sequence data to improve treatment outcomes.

Associate Professor

An evolutionary geneticist working on mechanisms for maintaining genome integrity.

Director, Computational Sciences

My interest is to develop principled methods to solve biological problems using quantitative methods from bioinformatics, machine learning, data science, and mathematics. In our group, we apply these computational methods to build predictive models to support cancer precision medicine and to understand the molecular mechanisms leading to diseases.

Assistant Professor

Interrogating the host immunity, microbiome and their interface using different engineering tools in the context of infectious diseases, autoimmunity and cancer.

Associate Professor

A Director of JAX's Nathan Shock Center of Excellence in the Basic Biology of Aging with expertise in the experimental design of large-scale studies of aged, genetically-diverse mice.

Professor

Specializes in pediatric brain and bone tumor research. Clinical interests include neuro-oncology, solid tumors, and osteosarcoma.

Scientific Director JAXGM and Professor

Studies structural genomic variation in human biology, evolution and disease.

Associate Professor

Metabolomics for precision medicine; ImmunoMetabolomics and multi-omics modeling of immune system. This revolutionary information fills a major gap between genome and environment, with broad applications to diseases and precision medicine.

Professor

Conducts research focused on the functional genomics of breast cancer through an exploration of the entire genomic space.

Associate Research Scientist

Studies critical genomic changes implicated in ovarian and breast cancers.

Associate Professor

Conducting research to elucidate and compare the transcriptional network structure and dynamics driving organogenesis.

Associate Professor

Develops novel mouse models of human disease and provides these resources to the scientific community. Employs conditional mutagenesis and forward genetics to interrogate the role of individual genes in development and disease.

Associate Professor

 Uses diverse tools like genomics and synthetic biology to investigate our microbiome’s role in our health and engineer therapeutics.

Director, Jax Cancer Center and Professor

Conducts research to understand how vaccines work and to define precisely the immune mechanisms that underlie vaccination, with a focus on cancer immunotherapies.

Professor

The Paust laboratory is interested in the development and testing of novel immunotherapies that elicit clinically relevant Natural Killer cell-mediated anti-pathogen or anti-tumor immunity.

Associate Professor

Focuses on comparative and functional mammalian genomics, reproductive development and stem cell biology.

Assistant Professor

Focuses on comparative and functional mammalian genomics, reproductive development and stem cell biology.

Associate Professor

Develops and enhances the Gene Expression Database (GXD), which captures, integrates and displays mouse developmental expression data generated world-wide.

Professor

Develops algorithms and software for the analysis of exome and genome sequences.

Professor

Studies cell-type composition in human solid tumors directly and derive models from these for functional analyses.

JAX Chief Medical Officer, Medical Director MCGI

Provides direction, leadership and strategy for JAX’s translational and clinical research activities and clinically-oriented operations.

Professor

Researches the genetic basis for immunological tolerance. Generating anti-tumor immune responses requires the transient induction of a form of autoimmunity.

Professor

Investigates human immunological diseases and malignancy through the development and leveraging of novel humanized mouse models.

Professor, Cellular Engineering

Exploits new genome-editing technology to study gene function and to model disease in human stem cells.

Professor

Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation.

Associate Professor

Develops computational models using genome datasets to study gene regulation and identify hypotheses for genomic medicine.

Professor

Researches the mechanisms of human T cell differentiation, activation and regulation in the contexts of normal immune response, diseases and aging.

Assistant Professor

Employs genomic and computational approaches to investigate how the immune response shapes brain tumor development.

Assistant Professor

Investigates mechanisms of drug resistance in hematological malignancies with the main goal to develop new therapeutic strategies and providing a blueprint for clinically relevant biomarkers.

Associate Professor

Provides expertise in mitochondrial control of innate immunity and inflammation  enabling studies of how the mitochondrial-innate immune axis contributes to genetic disorders, aging, and cancer.

Professor and Deputy Director, Jax Genomic Medicine

Leads the research and clinical genome sequencing groups.

Research Scientist

Researches inner ear development and the genetics underlying vestibular function dysfunction, as well as dwarfism and skeletal malformation.

Janeway Distinguished Chair and Professor of Mammalian Genetics

Conducts research to better understand the mechanisms that regulate germline stem cell fate.

Professor, The Bernard and Lusia Milch Endowed Chair

Develops computational strategies using genetic data to understand complex genetic systems involving multiple genes and environmental factors.

Principal Computational Scientist

Development of approaches and resources for the analysis, visualization and functional interpretation of large-scale immunological profiling datasets.

Professor, The Ann Watson Symington Chair in Addiction Research and Senior Director, Integrative Data Science

Develops software tools and resources for multi-species data integration in the study of health and disease and researches the genetic and biological basis for relationships among behavioral traits including addiction and other behaviors.

Professor, Karl Gunnar Johansson Chair

Employs a systems approach to investigate the genetics of health and disease and complex disease-related traits in the mouse.

Research Scientist

My research focuses on germ cell tumors (GCTs), a tumor type that occurs in pediatric and young adults. My focus in GCTs is around the developmental origins of GCTs and identifying new diagnostic and therapeutic targets. Additionally, I have an interest in utilizing pluripotent stem cells to model disease.

Professor

Researches the genetics of aging and lifespan, seeking to understand the basic mechanisms of aging, and adult stem cells, with the goal of delaying normal aging processes.

Research Scientist

Wide array of research interests includes infectious diseases, immune disorders and cancer pathogenesis.

Senior Research Scientist

Provides database development and web delivery for the Mouse Genome Informatics consortium.

Professor

Regulation of mammalian development and adult tissue homeostasis by growth and differentiation factors.

Associate Director of Machine Learning & Imaging Services

Integrative analysis of multi-omics data; integrative cross-species analysis of multi-omics data; AI and machine learning method development for and applications to bio-medical fields; image analysis.

Senior Research Scientist

Leads the software and database development teams that support a number of critical data resources.

Senior Research Scientist

Computational Oncology studies that integrate clinical, genomic, and imaging data to explore the dynamics of tumor heterogeneity and evolution in response to treatment.

Professor

Veterinary pathologist contributing to many aspects of disease research at JAX, with a research program focusing on genetic skin diseases.

Research Scientist

Research into lung development and role of miRNAs to better understand cancer, other lung diseases.

Associate Research Scientist

Currently researching the microenvironment of breast cancer, in order to develop new strategies of immunotherapy.

Associate Research Scientist

The importance of understanding the role of vaccinations and the ways in which they can be improved.