Tools & Resources

hΑβSAA

Expresses humanized Aβ1-42 with Swedish, Arctic and Austrian mutations.Read more

LOAD3 (late-onset AD 3)

Expresses humanized Aβ1-42, APOE4 and MAPT of H1 haplotype.Read more

Wild-derived AD panel

Amyloid strains that incorporate mouse natural genetic diversity:

B6.APP/PS1
WSB.APP/PS1
PWK.APP/PS1

AD-BXD panel

Alzheimer's disease mouse reference:

AD-BXD 2
AD-BXD 65

Emerging Models being created by CADR investigators and collaborators

All mouse models developed by MODEL-AD are made available from the JAX mouse repository.  All models are available for pharma and biotech use.

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Datasets and other resources

All datasets developed by MODEL-AD are available from the AD Knowledge Portal.

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In addition to Alzheimer’s disease mouse models, The Jackson Laboratory also offers human induced pluripotent stem cell (hiPSC) lines carrying Alzheimer’s disease-associated mutations - providing complementary tools for translational research.