Envision™: Supporting Better Decisions in Animal Welfare

Envision delivers unprecedented insights into animal health, with a continuous and non-invasive approach to on-study mouse monitoring. Adoption of the Envision platform reduces animal handling, expands oversight without extra staff, and enables early detection of health concerns.

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Limitations of Conventional
Assessment Methods

Conventional assessment methods for mice carry fundamental limitations:

• Gaps in Visibility: Manual checks provide only snapshot moments, missing critical continuous health and behavioral insights that occur between episodic assessments.
• Wasted Resources: Manual handling and observation create an artificial environment with increased variation that can result in extended studies and larger-than-necessary cohorts.
• Reactive Interventions: Significant handling causes significant stress and potentially alters their natural behaviors leading to unclear outcomes, confounded studies and repeated studies.

HealthSense: Objective Non-Invasive Health Monitoring

Envision tackles these challenges through its HealthSense app. This feature provides highly sensitive, continuous, objective, and non-invasive monitoring of on-study mouse health and behavior, enabling earlier detection of illness, improved welfare, richer study data, and greater reproducibility across preclinical models.

HealthSense offers graphical representations of individual and cage-level activities, including activity, distance traveled, drinking, feeding, and social distance for each mouse, facilitating comprehensive comparative analysis.

Enhanced Health and Physiology Monitoring through Comprehensive
Data Collection

Envision™ is innovating research methodology by continuously capturing digital measures beyond conventional capabilities:

• Comprehensive Tracking: Advanced machine learning and digital home-cage technology enable continuous, high-precision monitoring of behavioral and physiological parameters, revealing insights beyond conventional episodic assessments.
• Proactive Health Management: Real-time, non-invasive surveillance detects subtle physiological and behavioral changes, facilitating early intervention and optimizing colony health and research outcomes.

Integrated Research Capabilities:

• 24/7 remote monitoring with automated alerts
• Comprehensive data streaming
• Collaborative research platform for phenotype observation and health tracking

More Reproducible and Translatable Science Supporting the 3Rs

Envision™ reimagines ethical research methodologies:

• Replacement: Minimize the need for invasive manual observation. Envision's continuous monitoring reduces reliance on manual interventions, providing comprehensive data without additional animal handling.
• Refinement: Enhance animal welfare through minimal disturbance. Envision's 24/7 monitoring allows researchers to track animal health and behavior with unprecedented precision, while minimizing stress-inducing interactions.
• Reduction: Decrease the number of animals required in research studies. By capturing more detailed, continuous data, researchers can obtain more insights from fewer animals, reducing overall animal usage.

Validated Data Measures

Continuous monitoring of relevant validated digital measures ensures early detection of health issues without physical inspection or colony entry.

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